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Preface

Pharmacology has undergone major intellectual changes in the recent years and has become
increasingly important to all medical, dental and other health professionals. The graduate
students of dentistry may have to handle medical emergency during various dental
procedures on the dental chair. Besides this, dentists have to look into various drug
associated interactions. The broad goal of teaching pharmacology to undergraduate
students is to inculcate rational and scientific basis of therapeutics keeping in view the
dental curriculum and profession. A sincere attempt has been made to present a complete
text for undergraduate students of dentistry as per the new syllabus requirement (Dental
Council of India, BDS course regulation, 2006).
The book is divided into thirteen sections, initial sections cover the general and
autonomic pharmacology, followed by other sections of drug acting on different body
systems. A detailed section is devoted only to dental pharmacology which covers all agents
used in pharmacotherapy of dental conditions. The last section covers vaccine, sera and
other immunological agents and drugs used in skin disorders. The chapters have been
arranged in such a way that knowledge gained from initial chapters will be helpful to
students for understanding subsequent chapters. The appendix contains the list of newly
approved and banned drugs in India.
The classification adopted in the books provides pharmacological distinction among
latest drugs with doses and routes of administration along with leading trade name(s)
available in Indian market, but it should not be construed as the recommendation of those
particular brands.



(viii)

Thanks are due to New Age International (P) Ltd., N. Delhi for their keen interest and
attention in bringing out this book in its present form. Further, I am indebted to all my
friends and well wishers for their support and encouragement.
I would like to express my gratitude and indebtedness to all my family members for
their sacrifice, affection and inspiration throughout the present work.
New Delhi

Surender Singh


(ix)

Contents

Preface

(vii)

SECTION 1
General Principles of Pharmacology
1.1 Sources and Nature of Drug Dosage Form

3

1.2 Prescription Writing

15


1.3 Rational Use of Drugs & Drug Laws

19

1.4 Pharmacokinetics
(Absorption, Distribution, Metabolism and Excretion of Drugs)

25

1.5 Pharmacodynamics (Mode of Action of Drugs)

39

1.6 Adverse Drug Reactions

47

1.7 Drug Interactions

51

SECTION 2
Drugs Acting on CNS
2.1 General Anaesthetics
2.2 Sedative & Hypnotics

61
69

2.3 Narcotic Analgesics (Opioids)

2.4 Non-Narcotic Analgesics (NSAID’s)

75
83



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