Chapter 089. Pancreatic Cancer (Part 5) pptx
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Chapter 089. Pancreatic Cancer
(Part 5)
Figure 89-2
Survival by adjuvant chemotherapy. Kaplan-
Meier estimates of survival
from the European Study Group for Panc
reatic Cancer 1 (ESPAC1) trial for the
comparison of adjuvant chemotherapy versus no adjuvant chemotherapy (CT) in
patients with resected pancreatic cancer (hazard ratio for death, 0.71; 95%
confidence interval, 0.55 to 0.92; p = .009). (Reprinted with per
mission from JP
Neoptolemos, DD Stocken, H Friess, et al: A randomized trial of
chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N
Engl J Med 350:1200–
1210, 2004. Copyright 2004, Massachusetts Medical
Society.)
Further Readings
Alexakis N et al: Current standards of surgery for pancreatic cancer. Br J
Surg 91:1410, 2004 [PMID: 15499648]
Barugola G et al: The determinant factors of recurrence following resection
for ductal pancreatic cancer. JOP 8(Suppl 1):132, 2007
Chua YJ,
Cunningham D: Chemotherapy for advanced pancreatic cancer.
Best Pract Res Clin Gastroenterol 20:327, 2006 [PMID: 16549331]
DiMagno EP et al: AGA technical review on the epidemiology, diagnosis,
and treatment of pancreatic ductal adenocarcinomas. America
n
Gastroenterological Association. Gastroenterology 117:1464, 1999 [PMID:
10579989]
Greene FL, Page DL (eds.): Exocrine Pancreas,
AJCC Cancer Staging
Manual
, 6th ed, New York, Springer, pp 157–164, 2002
Neoptolemos JP et al: A randomized trial of che
moradiotherapy and
chemotherapy after resection of pancreatic cancer. N Engl J Med 350:1200, 2004
[PMID: 15028824]
Willett CG et al: Locally advanced pancreatic cancer. J Clin Oncol
23:4538, 2005 [PMID: 16002845]
Bibliography
Goggins M: Molecular m
arkers of early pancreatic cancer. J Clin Oncol
23:4524, 2005 [PMID: 16002843]
