Pediatric emergency medicine trisk 4533 4533
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there is now considerable recent experience with the use of these antibiotics for
selected serious pediatric infections. Furthermore, the risk of morbidity and
mortality from these biologic agent–induced diseases far outweighs the minor
risks (tendinopathy with fluoroquinolones, dental staining with tetracyclines)
associated with short-term pediatric use of these medications. In fact,
ciprofloxacin, levofloxacin, and doxycycline have lower risk of these adverse
effects and are approved by the U.S. Food and Drug Administration (FDA) for
use in children for the treatment and prophylaxis of anthrax and plague following
inhalational exposure (i.e., in the context of terrorism).
