Pediatric emergency medicine trisk 2379 2379
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e-TABLE 94.14
TREATMENT OF LYME DISEASE SEPTIC ARTHRITIS
Age
Type
<8 yrs of age
≥8 yrs of age
Initial
Amoxicillin 50 mg/kg/day in
three divided doses
(maximum 500 mg/dose)
for 28 days
Recurrent or
persistent
Ceftriaxone 50–75 mg/kg
(maximum dose 2 g/day) as
a single daily dose for 14–
28 days
14–28 days
or
Same regimen as above for
initial treatment of arthritis
Doxycycline 2.2 mg/kg/dose
twice daily (maximum 100
mg/dose) for 28 days
or
Amoxicillin 50 mg/kg/day in
three divided doses
(maximum 500 mg/dose)
for 28 days
Same as for younger children
Data from Wormser GP, Dattwyler RJ, Shapiro ED, et al. The clinical assessment, treatment, and prevention
of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the
Infectious Diseases Society of America. Clin Infect Dis 2006;43:1089–1134. Newer guidelines to be
published in the winter of 2020.
