platelets. Takes
time to arrange;
generally unable
to obtain in the
ED
Single donor
Preferred c
No
Premedication
Possible
Possible
Quantity
General
guidelines:
1 unit <10 kg
3 units 10–30 kg
6 units 30–80 kg
8 units >80 kg
a Not
Highly transfused
population are at
risk for reactions
Acetaminophen if
h/o febrile
reactions
Diphenhydramine if
h/o allergic
reaction
Hydrocortisone if
h/o allergic
reaction despite
diphenhydramine
or very severe
allergic reaction
pRBC elective
Volume-reduced
transfusion:
platelets in
patients very
10–15 mL/kg or 2
sensitive to
units for >50-kg
volume overload
patient
decrease
effectiveness of
transfusion
Continuous infusion
for plateletrefractory patient
with ongoing
significant
bleeding
required if type previously performed at blood bank.
product unnecessary if product has been leukoreduced.
c Apheresis platelets from a single donor preferred.
b CMV-negative