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Pediatric emergency medicine trisk 2411 2411

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Diagnostic
criteria

Symptoms, laboratory
findings

Absolute

Treponema pallidum
visualized
Major clinical Condylomata lata

Osteochrondritis,
perichondritis

Snuffles

Minor clinical Fissures

Cutaneous lesions

Mucous patches
Hepatomegaly, splenomegaly

Details
Dark field microscopy
Raised, nontender, moist
lesions on skin; highly
infections (contact
precautions should be used)
Most common manifestation


(60–80%): humeral and
femoral involvement most
common. Serrated
appearance to epiphysis on
long-bone XRs
Appears between 1 and 12
wks of age; severe longlasting whitish to bloody
nasal discharge
Fissures around mouth, nares,
anus; easily bleed, heal with
scarring. While not a
common finding, fissures
are somewhat specific (but
not pathognomonic) for
congenital syphilis
Maculopapular rash more
common on hands/feet; can
be bullous, and if present at
birth is often disseminated
(pemphigus syphiliticus);
highly infections (contact
precautions should be used)
Painless patches on mouth,
genitals
Hepatomegaly almost



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