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FIGURE 69.14 Infant with acute hemorrhagic edema of infancy.
Hemangiomas
Hemangiomas of infancy (infantile hemangiomas) represent benign vascular
tumors that are present in approximately 3% of newborns and up to 10% of all
infants. These are seen more frequently in premature and low–birth-weight
infants and occur more commonly in girls than in boys. Superficial lesions
possess a red color, resembling a strawberry or raspberry. Deep lesions appear
soft, compressible, and often are faintly bluish. Mixed lesions may show features
of both superficial and deep hemangiomas. A precursor lesion may or may not be
noticeable immediately at birth. They typically undergo an early rapid growth
phase between 5 and 8 weeks old, continue to proliferative phase during the first
4 to 6 months, plateau in growth during the second 6 months, and then begin a
slow process of involution that lasts a few years. Beta-blockers, specifically
systemic propranolol and topical timolol, are used to treat severe hemangiomas of
infancy. Potential complications include bradycardia, hypotension, hypoglycemia,