Regimen A
Extended
parenteral
treatment
Regimen B a
Extended
parenteral
treatment
Initial therapy
Subsequent
therapy
Comments
Cefotetan 2 g IV
every 12 hrs
or
Cefoxitin 2 g IV
every 6 hrs
with
Doxycycline 100
mg po or IV
every 12 hrs
Doxycycline 100 Oral doxycycline is
mg po bid to
preferred to avoid
complete 14
infusion pain
days of
Parenteral treatment
therapy
may be stopped
24 hrs after
clinical
improvement
Clindamycin 900
Doxycycline 100 Clindamycin is
mg IV every 8 hrs
mg po bid
preferred for oral
treatment of
with
or
tuboovarian
Gentamicin 2 mg/kg Clindamycin 450
abscess
and then 1.5
mg po qid to
Parenteral treatment
mg/kg IV or IM
complete 14
may be stopped
every 8 hrs
days of
24 hrs after
(single daily
therapy
clinical
dosing may be
improvement
substituted)
Regimen C
Combined
Ceftriaxone 250 mg Doxycycline 100 Ceftriaxone has
parenteral/oral
IM
mg po bid for
better coverage
treatment
14 days
than cefoxitin
PLUS
against Neisseria
Azithromycin 1 g
gonorrhoeae
orally in a single
Adding
dose or
metronidazole
doxycycline 100
(500 mg orally
mg orally twice
twice a day for 14
daily for 7 days a
days) will treat
or
the bacterial
vaginosis