Andersons pediatric cardiology 1381
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cardiactumor.Thisstudycharacterizesthe
incidence,progression,andclinical
consequencesofrhabdomyomasinalarge
cohortofpatientswithtuberoussclerosis
complex..
AwF,GoyerI,RaboissonMJ,etal.Accelerated
cardiacrhabdomyomaregressionwith
everolimusininfantswithtuberoussclerosis
complex.PediatrCardiol.2017;38(2):394–400.
RegressionofrhabdomyomasinresponsetomTOR
inhibitorssuchaseverolimuswasfirstreported
in2011.Thisdiscoveryrepresentedamajor
advanceinthetreatmentofpatientssymptomatic
fromrhabdomyomas.Thisretrospectivereview
offourinfantcasesfoundtumorregressionto
occurnearly12timesfasterthaninhistorical
controls..
BeroukhimRS,PrakashA,Valsangiacomo
BuechelER,etal.Characterizationofcardiac
tumorsinchildrenbycardiovascularmagnetic
resonanceimaging:amulticenterexperience.J
AmCollCardiol.2011;58(10):1044–1054.
CardiacMRIhasemergedasapowerfultoolinthe
diagnosisofpediatriccardiactumors,inlarge
partduetoitsabilitytopredicttumortypebased
onsignalcharacteristics.Thismulticenterstudy
describestheimagingcharacteristicsof
pediatriccardiactumorsbasedon78caseswith
confirmedhistologicdiagnosis..
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