Andersons pediatric cardiology 1778
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FIG.67.10 Kaplan-Meiersurvivalcurveoutto25yearsafterheart
transplantationinchildhoodstratifiedbyageatthetimeoftransplantation.
(FromtheregistryoftheInternationalSocietyofHeartandLung
Transplantation.JHeartLungTransplant.2016;35(10):1185–1195.)
FIG.67.11 ConditionalKaplan-Meiersurvival,conditionalonsurvivalto1
yearsubsequenttohearttransplantation,stratifiedbyageat
transplantation.(FromtheregistryoftheInternationalSocietyofHeartand
LungTransplantation.JHeartLungTransplant.2016;35(10):1185–1195.)
FIG.67.12 ConditionalKaplan-Meiersurvivalconditionalonsurvivalto1
yearafterhearttransplantationforthemostrecenterafrom2004to2014
stratifiedbyageattransplantation.(FromtheregistryoftheInternational
SocietyofHeartandLungTransplantation.JHeartLungTransplant.
2016;35(10):1185–1195.)
Lookingmorecloselyattheeffectofera,significantimprovementsinsurvival
continuetobenoted,primarilyrelatedtoareductioninmortalityimmediately
subsequenttotransplantation(seeFig.67.9).Conditionalsurvivalforthe
differentagegroupswithintheperiodfrom2004to2014amplifiesthe
differencebetweeninfants,children,andadolescents,withinfantsandchildren
havingaconditionalsurvivalat10yearsof83%,whereasthesurvivalof
adolescentsisapproximately65%(seeFig.67.12).
Thediagnosisbeforetransplantationalsomodifiessurvival.Thereisa
significantlyhigherearlymortalityforpatientswithcongenitalheartdisease
versusthosetransplantedforcardiomyopathy,andthisistrueacrossallage
groups.2PosttransplantoutcomesforpatientsbridgedwithVADsupportare
equivalenttooutcomeswithoutmechanicalsupportinthecurrenteraand
significantlybetterthanoutcomesforpatientsbridgedwithECMOsupport2,9
(Fig.67.13).
