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pneumoniae . Mycoplasma-induced rash and mucositis (MIRM) has been
proposed as a descriptor for mucocutaneous eruptions triggered by mycoplasma
infection. Treatment is supportive and directed at the underlying infection.
Toxic shock syndrome is a toxin-mediated disease that has oral manifestations
including oropharyngeal erythema and strawberry tongue as well as systemic
findings.
Patients with neutropenia (e.g., secondary to chemotherapy) are susceptible to
mucositis, often presenting with painful ulcers, exudate, and pseudomembranes
on the gingivae and buccal mucosa, as well as fetid breath. Patients with
hematologic malignancies or history of stem cell transplantation are at risk for the
life-threatening fungal infection palatal mucormycosis, most commonly
presenting as a black necrotic patch on the hard palate.
Oral changes in Kawasaki disease, a potentially life-threatening disorder,
include red, dry, cracked lips, erythematous oropharynx, and strawberry tongue (
Fig. 52.5 ).
The inflammatory lesions of Crohn disease may occur in any portion of the
gastrointestinal tract. Oral lesions, seen most often in adolescents and young
adults, include ulcers, polypoid papulous hyperplastic mucosa, and edema of the
lips, gingiva, vestibular sulci, and buccal mucosa. Chronic, recurrent ulcers
surrounded by erythema and gray exudate are found throughout the oral cavity in
patients with Behỗet syndrome.