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Cephalosporins are not as effective as high-dose amoxicillin against S.
pneumonia and should not be chosen as first-line therapy in patients who can take
amoxicillin. Azithromycin and other macrolides have limited efficacy against S.
pneumoniae and H. influenza and should not be used for the treatment of AOM.
A 10-day course of antibiotics is recommended for children less than 24
months of age with AOM. In patients with mild or moderate AOM who are over
24 months of age, a 7-day course of antibiotics is adequate. Evidence does not
support routine 10- to 14-day follow-up for patients after treatment of AOM. A
majority of children will have persistent middle ear fluid 2 weeks after the start of
treatment, and almost half will still have fluid at 1 month. Children with
persistent symptoms after treatment for AOM should follow up with their primary
care provider. Oral decongestants, intranasal decongestants, oral antihistamines,
and steroid preparations are ineffective in the treatment of AOM and OME and
should not be prescribed.
Persistent middle ear fluid without acute symptoms (OME) may be associated
with a conductive hearing loss. Though the evidence for a long-term impact of
mild and transient conductive hearing loss on otherwise normal children is weak,
those in whom there is concern for developmental or cognitive delays should be
followed more closely. Children with persistent middle ear effusion should not
generally receive antibiotic prophylaxis. There is a modest, short-term benefit of
antibiotic prophylaxis in reducing episodes of recurrent AOM. Antibiotic
prophylaxis is not recommended for most children with recurrent AOM.
Tympanostomy tube placement is a decision that is best made by primary care
providers in consultation with otolaryngologists, and should be considered if a
child has had three documented episodes of AOM within 6 months or four
episodes within the preceding year.
OTORRHEA
Children with AOM and perforation improve more quickly when treated with oral
antibiotic therapy rather than topical therapy. Many experts also recommend
antibiotic ear drops in this setting, though there is little evidence for this dual