Pediatric emergency medicine trisk 1030 1030
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Rhabdomyosarcoma is a rare malignant tumor that can present in the oral
cavity. These fast-growing, ulcerative lesions may present with bleeding.
Associated signs and symptoms are usually attributed to the mass lesion or
obstructive sequelae. Other malignancies such as fibrosarcoma, epidermoid
carcinoma, carcinoma of the parotid, minor salivary gland malignancies,
osteosarcoma, histiocytosis, and lymphoma may also present as intraoral mass
lesions. Mucosal neuromas can be a presenting sign of multiple endocrine
neoplasia type 2B.
FIGURE 52.4 Melanotic neuroectodermal tumor of infancy.
Oral Lesions Associated With Systemic Disease
Stevens–Johnson syndrome is a potentially life-threatening illness involving
necrosis and detachment of the epidermis of skin and mucous membranes. It is
most commonly triggered by medications, although infection may also be
implicated. Oral lesions include erythema, erosions, scabs, and pseudomembranes
often preceded by fever, malaise, and dysphagia. Removal of the offending
medication is key, followed by intensive supportive care. Erythema multiforme,
classically presenting with polychromatic target lesions, can also demonstrate
mucosal involvement, including erythema, erosions, or bullae. It is commonly
triggered by infections, including herpes simplex virus or Mycoplasma
