Pediatric emergency medicine trisk 1374 1374
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FIGURE 70.15 Kaposi varicelliform eruption. Note the crusted vesicles and pustules
concentrated in areas where the pre-existing eczema has been active.
Kaposi Varicelliform Eruption
KVE is a collective term that indicates an acute, often rapidly progressive,
viral secondary infection of an underlying inflammatory skin condition (
Table 70.2 ). When herpes simplex virus, enterovirus, or vaccinia virus
secondarily infects the skin in atopic dermatitis, the condition is referred to
as eczema herpeticum (EH), eczema enteroviricum (coxsackium), or eczema
vaccinatum, respectively. Less commonly, inflammatory diseases such as
psoriasis, PRP, or blistering skin diseases like pemphigus vulgaris,
pemphigus foliaceus, keratosis follicularis (Darier disease), or benign
familial pemphigus (Hailey–Hailey disease) can become infected, usually
with herpes simplex virus and less commonly, varicella zoster virus.
Similarly, contact dermatitis, sunburn, or other more acute skin barrier
damage can provide a temporary opportunity for the same phenomenon to
occur outside of a chronic skin condition.
The hallmarks of the condition are the acute onset and rapid progression
of viral skin lesions. Initially localized vesicles or pustules will rapidly
