heartdisease.JHeartLungTransplant.
2017;36(11):1209–1216.
ThisrecentstudyfromtheBerlinHeartExcor
PediatricStudydatasethighlightsthechallenges
ofmechanicalsupportinpatientswithCHD.
OveralltheoutcomesofCHDpatientswere
worsethanpatientswithcardiomyopathyand
amongCHDpatients,end-organdysfunction,
youngage,priorECMO,andpriorcongenital
heartsurgerywereassociatedwithincreased
mortality.
RossanoJW,LortsA,VanderPluymCJ,etal.
Outcomesofpediatricpatientssupportedwith
continuous-flowventricularassistdevices:A
reportfromthepediatricinteragencyregistryfor
mechanicalcirculatorysupport(PediMACS).J
HeartLungTransplant.2016;35(5):585–590.
ThisrecentstudyfromPedimacsdescribesthe
outcomesofchildrensupportedwithcontinuous
flowVADs.Overall,theoutcomesinchildren
wereexcellentandsimilartoadultpatientsthat
wereimplantedasabridgetotransplantation.
AlthoughmostoftheVADswereplacedin
adolescents,anincreasingnumberarebeing
placedinsmallerchildren.
References
1.BlumeED,NaftelDC,BastardiHJ,etal.
Outcomesofchildrenbridgedtoheart
transplantationwithventricularassistdevices:a
multi-institutionalstudy.Circulation.
2006;113(19):2313–2319.
2.RossanoJW,CherikhWS,ChambersDC,etal.
Theregistryoftheinternationalsocietyforheart
andlungtransplantation:twentiethpediatric
hearttransplantationReport-2017;Focustheme:
allograftischemictime.JHeartLung
Transplant.2017.
3.RossanoJW,KimJJ,DeckerJA,etal.
Prevalence,morbidity,andmortalityofheart
failure-relatedhospitalizationsinchildreninthe
UnitedStates:apopulation-basedstudy.JCard
Fail.2012;18(6):459–470.
4.BlumeED,VanderPluymC,LortsA,etal.
Secondannualpediatricinteragencyregistryfor
mechanicalcirculatorysupport(Pedimacs)
report:Pre-implantcharacteristicsandoutcomes.
JHeartLungTransplant.2018;37(1):38–45.
5.RossanoJW,ShaddyRE.Heartfailurein
children:etiologyandtreatment.JPediatr.
2014;165(2):228–233.
6.EverittMD,SleeperLA,LuM,etal.Recovery
ofechocardiographicfunctioninchildrenwith
idiopathicdilatedcardiomyopathy:resultsfrom
thepediatriccardiomyopathyregistry.JAmColl
Cardiol.2014;63(14):1405–1413.
7.AlexanderPM,DaubeneyPE,NugentAW,etal.
Long-termoutcomesofdilatedcardiomyopathy
diagnosedduringchildhood:resultsfroma
nationalpopulation-basedstudyofchildhood
cardiomyopathy.Circulation.
2013;128(18):2039–2046.
8.Wittlieb-WeberCA,LinKY,ZaoutisTE,etal.
Pediatricversusadultcardiomyopathyandheart
failure-relatedhospitalizations:avalue-based
analysis.JCardFail.2015;21(1):76–82.
9.KirklinJK,NaftelDC,KormosRL,etal.Fifth
INTERMACSannualreport:riskfactoranalysis
frommorethan6,000mechanicalcirculatory
supportpatients.JHeartLungTransplant.
2013;32(2):141–156.
10.KirklinJK,NaftelDC,PaganiFD,etal.Seventh
INTERMACSannualreport:15,000patientsand
counting.JHeartLungTransplant.
2015;34(12):1495–1504.
11.AdachiI,KhanMS,Guzman-PrunedaFA,etal.
Evolutionandimpactofventricularassistdevice
programonchildrenawaitingheart