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pustules, in addition to laboratory evaluation, will help distinguish AGEP from
DHR. Eliciting either a personal or family history of psoriasis or a history of a
high-risk medication can help favor a diagnosis of either pustular psoriasis or
AGEP, respectively.
AGEP generally resolves with desquamation within 4 to 10 days after stopping
the drug. Topical steroids and oral antihistamines can provide symptomatic relief
if needed.
FIGURE 68.5 Erythema caloricum: back. (Courtesy of Benjamin Barankin, MD, Edmonton,
Alberta, Canada. In: Stedman’s Medical Dictionary for the Health Professions and Nursing . 7th
ed. Wolters Kluwer: Philadelphia, PA; 2012.)
VESICULOBULLOUS
Fixed Drug
Fixed drug eruption generally appears as a sharply demarcated erythematous to
dusky, edematous oval, or circular plaque ( Fig. 68.6 ). The plaques may become
bullous. Lesions can appear anywhere, but the lips, face, hands, feet, and genitals
are commonly affected. They often leave hyperpigmentation that may take