Pediatric emergency medicine trisk 0541 0541
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drugs, opiate receptor agonists (e.g., loperamide), reduce intestinal mobility and
delay transit time, thereby prolonging course of illness. Toxic side effects of these
medications include lethargy and paralytic ileus. Antisecretory drugs like bismuth
subsalicylate have limited efficacy and have potential for salicylate toxicity.
Adsorbents (e.g., hydrated aluminomagnesium silicates and kaolin-pectin), while
having potential to bind digestive mucus and reduce water loss, have not been
shown to reduce diarrheal duration, frequency, or volume.
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